Pili de type IV

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Pulling together with type IV pili.

Type IV pili are an efficient and versatile device for bacterial surface motility. They are widespread among the beta-, gamma-, and delta-proteobacteria and the cyanobacteria. Within that diversity, there is a core of conserved proteins that includes the pilin (PilA), the motors PilB and PilT, and various components of pilus biogenesis and assembly, PilC, PilD, PilM, PilN, PilO, PilP, and PilQ....

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Type IV pili in Gram-positive bacteria.

Type IV pili (T4P) are surface-exposed fibers that mediate many functions in bacteria, including locomotion, adherence to host cells, DNA uptake (competence), and protein secretion and that can act as nanowires carrying electric current. T4P are composed of a polymerized protein, pilin, and their assembly apparatuses share protein homologs with type II secretion systems in eubacteria and the fl...

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Type IV pili—a numbers game

Type IV pili are long polymers located on the surface of a wide variety of bacterial cells, including the pathogenNeisseria meningitidis. They are responsible for a diverse range of functions, including adhesion, motility and natural transformation. In this issue of The EMBO Journal, Imhaus and Duménil show that two minor pilins, PilX and PilV, exert some of their effects by changing mean surfa...

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Bacteria use type-IV pili to slingshot on surfaces.

Bacteria optimize the use of their motility appendages to move efficiently on a wide range of surfaces prior to forming multicellular bacterial biofilms. The "twitching" motility mode employed by many bacterial species for surface exploration uses type-IV pili (TFP) as linear actuators to enable directional crawling. In addition to linear motion, however, motility requires turns and changes of ...

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How Bacteria Use Type IV Pili Machinery on Surfaces.

The bacterial type IV pilus (T4P) is a versatile molecular machine with a broad range of functions. Recent advances revealed that the molecular components and the biophysical properties of the machine are well conserved among phylogenetically distant bacterial species. However, its functions are diverse, and include adhesion, motility, and horizontal gene transfer. This review focusses on the r...

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ژورنال

عنوان ژورنال: médecine/sciences

سال: 2009

ISSN: 0767-0974,1958-5381

DOI: 10.1051/medsci/2009255437